Posters and Publications
Scientific Presentations and Publications
Edgewise presents original research on its science and therapeutic development at scientific and medical conferences, as well as in published peer-reviewed scientific journals.
Please contact us if you would like to learn more about the research presented here.
June 2023
EDG-5506: A Novel Approach to Protect Muscle in Duchenne Muscular Dystrophy
2023 PPMD Annual Conference
June 2023
EDG-5506: A Novel Approach Designed to Protect Muscle in Becker Muscular Dystrophy
2023 PPMD Annual Conference
March 2023
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy
The Journal of Clinical Investigation
March 2023
Effects of EDG-5506, a Fast Myosin Modulator, on Biomarkers of Muscle Damage and Function in Adults with Becker Muscular Dystrophy
2023 MDA Annual Clinical and Scientific Conference
March 2023
Targeting Fast Muscle Myosin: A Novel Approach to Protecting Muscle in the Dystrophinopathies
2023 MDA Annual Clinical and Scientific Conference Industry Forum
March 2023
Plasma Metabolic Profiling Suggests Enrichment of Glycolytic Pathways Over Fatty Acid Oxidation in Becker Muscular Dystrophy
2023 MDA Annual Clinical and Scientific Conference
March 2023
Effects of EDG-5506, a Fast Myosin Modulator, on Biomarkers of Muscle Damage and Function in Adults with Becker Muscular Dystrophy (BMD)
2023 MDA Annual Clinical and Scientific Conference
March 2023
Fast Skeletal Myosin Modulator EDG-5506 Confers Additional Protection to mdx Mice Receiving Glucocorticoid Treatment
2023 MDA Annual Clinical and Scientific Conference
March 2023
Characterization of Short- and Long-Term Proteomic Response to the Fast Skeletal Myosin Inhibitor, EDG-5506, in Becker Muscular Dystrophy (BMD)
2023 MDA Annual Clinical and Scientific Conference
March 2023
EDG-7500 (EDG-002), A First-in-Class Targeted Sarcomere Regulator that Preserves Intrinsic Myosin-Motor Function, Normalizes Systolic Function and Eliminates LVOT Obstruction in Cats with Hypertrophic Cardiomyopathy
American College of Cardiology (ACC) Annual Scientific Session & Expo 2023
February 2023
Development of a Model of the Patient Experience of Becker Muscular Dystrophy (BMD)
2023 International Conference on Duchenne and Becker Muscular Dystrophy
February 2023
EDG-5506: A Novel Approach to Protect Muscle in Duchenne and Becker Muscular Dystrophy
2023 International Conference on Duchenne and Becker Muscular Dystrophy
October 2022
Targeting Fast Muscle Myosin: A Novel Approach to Protecting Muscle in the Dystrophinopathies
2022 Annual Congress of the World Muscle Society
October 2022
EDG-5506 Targets Fast Skeletal Myosin to Protect Dystrophic Muscle and Reduce Muscle Damage Biomarkers in a Phase 1 Trial in Becker Muscular Dystrophy (BMD)
2022 Annual Congress of the World Muscle Society
October 2022
Clinical Development of EDG-5506 in Duchenne and Becker Muscular Dystrophy
2022 Annual Congress of the World Muscle Society
October 2022
Patient Reported Aspects of Becker Muscular Dystrophy from The Duchenne Registry a Comprehensive Registry for Duchenne and Becker Muscular Dystrophy (BMD)
2022 Annual Congress of the World Muscle Society
June 2022
EDG-5506: A Novel Approach to Protect Muscle in Duchenne Muscular Dystrophy
2022 PPMD Annual Conference
June 2022
EDG-5506: A Novel Approach to Protect Muscle in Becker Muscular Dystrophy
2022 PPMD Annual Conference
June 2022
Insights into the Becker Muscular Dystrophy Experience from the Duchenne Registry, a Comprehensive Registry for Duchenne and Becker Muscular Dystrophy
2022 PPMD Annual Conference
June 2022
EDG-5506: A Novel Approach to Protect Muscle in Duchenne and Becker Muscular Dystrophy
2022 PPMD Annual Conference
June 2022
Understanding the Becker Muscular Dystrophy (BMD) Experience from the Patient Perspective: It’s More Than Mild Duchenne
2022 PPMD Annual Conference
June 2022
Taking a New Approach to Protect Muscle in Duchenne and Becker Muscular Dystrophy: EDG-5506
New Directions Biology and Disease of Skeletal Muscle Conference
June 2022
Use of an Exercise Challenge System to Define a Universal Proteomic Signature of Muscle Injury in a Diverse Set of Adult Individuals with Inherited Myopathy
New Directions Biology and Disease of Skeletal Muscle Conference 2022
June 2022
Short-Term Proteomic Responses to the Fast Skeletal Myosin Inhibitor EDG-5506 in Becker Muscular Dystrophy
New Directions Biology and Disease of Skeletal Muscle Conference 2022
June 2022
EDG-5506 is a Selective Inhibitor of Fast Skeletal Muscle Myosin
New Directions Biology and Disease of Skeletal Muscle Conference 2022
June 2022
Skeletal myosin inhibitor EDG-5506 protects dystrophic muscle from contraction induced injury
New Directions Biology and Disease of Skeletal Muscle Conference 2022
May 2022
Manipulating the Dark Side of Muscle Adaptation for Therapeutic Gain
13th Annual GoldLab Symposium
March 2022
EDG 5506 Targets Fast Skeletal Myosin to Protect Dystrophic Muscle and Reduce Muscle Damage Biomarkers in a Phase 1 Trial in Becker Muscular Dystrophy
2022 MDA Clinical and Scientific Conference
March 2022
EDG-5506 Targets Fast Skeletal Myosin to Protect Dystrophic Muscle and Reduce Muscle Damage Biomarkers in a Phase 1 Trial in Becker Muscular Dystrophy
2022 MDA Clinical and Scientific Conference
March 2022
Modulating fast skeletal muscle contraction as a novel therapeutic strategy for muscular dystrophy
2022 MDA Clinical and Scientific Conference
March 2022
Use of an exercise challenge system to define a universal proteomic signature of muscle injury in a diverse set of adult individuals with inherited myopathy
2022 MDA Clinical and Scientific Conference
March 2022
A Novel Approach to Protecting Dystrophic Muscle by Targeting Fast Muscle Myosin: EDG-5506
2022 MDA Clinical and Scientific Conference
February 2022
Direct and Selective Myosin-Inhibition Stabilizes the Super-Relaxed State of Myosin and Blunts Post-Tetanic Potentiation in Fast-Skeletal Muscle
2022 Annual Meeting of the Biophysical Society
June 2021
Selective Inhibition of Fast Skeletal Muscle Myosin as a Novel Therapeutic Strategy for Muscular Dystrophy
2021 New Directions in Biology and Disease of Skeletal Muscle Conference
June 2021
Development of a Novel Therapeutic for Duchenne, Becker and other Muscular Dystrophies
2021 PPMD Annual Conference
May 2021
Elevation of fast but not slow troponin I in the circulation of patients with Becker and Duchenne muscular dystrophy
Muscle & Nerve, March 8, 2021
March 2021
Elevation of fast but not slow troponin I in the circulation of patients with Becker and Duchenne muscular dystrophy
MDA Clinical & Scientific Conference, March 16-18, 2021