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Edgewise

Edgewise Therapeutics

A Movement in Muscle

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    We are dedicated to transforming cardiovascular diseases.

    Learn More

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    • Cardiovascular Diseases

    All of us at Edgewise are committed to developing new medicines for people facing serious cardiovascular diseases with unmet medical needs.

    Explore our Pipeline

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Dedicated to transforming

cardiovascular
disease

Moved by the heart

From inertia to innovation. From possibility to promise. From unmet need to novel therapies.

At Edgewise, we’re bringing our unique expertise to develop novel therapeutics for serious cardiovascular diseases – with determination, integrity and a strong commitment to patients.

Learn more about how our science is driving a new understanding of cardiac diseases and its potential to transform human health.

Explore our pipeline

Our Focus:

Serious Cardiovascular Diseases With Life-limiting Impact

Hypertrophic Cardiomyopathy (HCM)

HCM is the most prevalent inherited cardiomyopathy. It is characterized by excessive thickening of the left ventricular wall, which can lead to life-altering symptoms and limitations in daily activities.

Learn More About HCM

Heart Failure (HF)

Heart failure, including heart failure with preserved ejection fraction (HFpEF), is a highly prevalent cardiovascular disease often associated with a stiffened heart muscle that can significantly impact daily life.

Learn More About HF

Inspired by
patients and families

We honor the experience of individuals and families living with and facing the challenges of serious cardiovascular disease. Our commitment to bringing life-changing medicines is inspired by their strength and courage.

Explore our commitment to patients and families

Science Driven.
Patient commitment.

Our science-driven culture places patients first as we start with their unmet need then work towards developing therapies to help address the significant challenges of serious cardiovascular diseases.

Experience our culture

Add muscle to your career

We built a company that’s inspirational, pioneering, science-forward and always reaching new heights. Learn more about what it’s like to work with us—globally or at our headquarters—and elevate your career to the next level.

See how we work

Latest News

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Aug. 24, 2026

Edgewise Therapeutics Announces Upcoming Late-Breaking Science Presentation at the European Society of Cardiology (ESC) Congress 2026

Read More about Edgewise Therapeutics Announces Upcoming Late-Breaking Science Presentation at the European Society of Cardiology (ESC) Congress 2026

Aug. 6, 2026

Edgewise Therapeutics Reports Second Quarter 2026 Financial Results

Read More about Edgewise Therapeutics Reports Second Quarter 2026 Financial Results

Jul. 13, 2026

Edgewise Therapeutics Completes Sale of Sevasemten for Up to $2.65 Billion, Strengthening Balance Sheet and Centering Company Focus on Cardiovascular Pipeline

Read More about Edgewise Therapeutics Completes Sale of Sevasemten for Up to $2.65 Billion, Strengthening Balance Sheet and Centering Company Focus on Cardiovascular Pipeline

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Edgewise Therapeutics
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In the Clinic

We are advancing novel precision therapeutics for serious cardiovascular disease.

Explore our pipeline

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