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Edgewise

Edgewise Therapeutics

A Movement in Muscle

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    • Disease Areas
    • Muscular Dystrophy
    • Hypertrophic Cardiomyopathy

    Learn more about how our science is driving a new understanding of muscle and its potential to transform human health.

    Explore Muscle

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    All of us at Edgewise are committed to developing new medicines for people facing serious muscle diseases with unmet medical needs.

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    We honor the experience of individuals and families living with and facing the challenges of serious muscle disease.

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    Our vision is to improve the lives of patients and families suffering from serious muscle diseases by building the world’s leading muscle-focused company.

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Welcome to

a movement
in muscle

Muscle moves us.

From inertia to innovation. From possibility to promise. From unmet need to novel therapies.

At Edgewise, we’re bringing our unique expertise and singular focus on muscle science to develop novel therapeutics for serious skeletal and cardiac muscle diseases – with determination, integrity and a strong commitment to patients.

But our movement in muscle doesn’t end there.

Learn more about how our science is driving a new understanding of muscle and its potential to transform human health.

Explore our science

Our Focus:

Serious Muscle Diseases With Life-limiting Impact

Cardiovascular Diseases

Advancing EDG-7500, a novel oral, selective cardiac sarcomere modulator for hypertrophic cardiomyopathy.

Learn More About HCM

Muscular Dystrophy

Exploring sevasemten, an orally administered first-in-class fast skeletal myosin inhibitor for Becker, Duchenne, and other muscular dystrophies.

Learn More About MD

Inspired by
patients and families

We honor the experience of individuals and families living with and facing the challenges of serious muscle disease. Our commitment to bringing life-changing medicines is inspired by their strength and courage.

Read their stories

Muscular thinking.
Courageous commitment.

Our science-driven culture places patients first as we start with their unmet need then work towards developing therapies to help address the significant challenges of serious muscle diseases.

Experience our culture

Add muscle to your career

We built a company that’s inspirational, pioneering, science-forward and always reaching new heights. Learn more about what it’s like to work with us—globally or at our headquarters—and elevate your career to the next level.

See how we work

Latest News

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May. 8, 2025

Edgewise Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights

Read More about Edgewise Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights

Apr. 2, 2025

Edgewise Therapeutics Announces Pricing of $200 Million Underwritten Offering of Common Stock

Read More about Edgewise Therapeutics Announces Pricing of $200 Million Underwritten Offering of Common Stock

Apr. 2, 2025

Edgewise Therapeutics Announces Positive Top-Line Results from Phase 2 CIRRUS-HCM Four-Week Trial of EDG-7500 in Hypertrophic Cardiomyopathy (HCM)

Read More about Edgewise Therapeutics Announces Positive Top-Line Results from Phase 2 CIRRUS-HCM Four-Week Trial of EDG-7500 in Hypertrophic Cardiomyopathy (HCM)

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Edgewise Therapeutics
  • Disease Areas
  • Science & Pipeline
  • Patients & Families
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Deep knowledge of integrated 
muscle physiology

Learn more about how our science is driving a new understanding of muscle and its potential to transform human health.

Explore our Science

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  • Disease Areas
    • Muscular Dystrophy
    • Hypertrophic Cardiomyopathy
  • Science & Pipeline
    • Pipeline
    • Sevasemten
    • EDG-7500
    • Clinical Trials
    • Posters & Presentations
  • Patients & Families
    • Support for Becker
    • Support for Duchenne
    • Support for HCM
    • Patient Stories
  • Company
    • Leadership Team
    • Careers
    • Contact Us
  • Investors & Media
    • Corporate Profile
    • News
    • Events & Presentations
    • Analyst Coverage
    • Stock Info
      • Stock Quote
      • Stock Chart
      • Historical Stock Quote
      • Investment Calculator
    • Financials
      • Quarterly Results
      • SEC Filings
    • Goverance
      • Governance Documents
      • Committee Composition
    • Resources
      • Investor FAQs
      • Investor Email Alerts
      • Investor Contacts